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Abstract: The article deals with the importance of the indicators of biological age for organization of the education process of physical education of university students. In practical physical education, determination of biological age via motor criteria is a basic element. Therefore, the authors of the article turn their attention to the chart “Test Yourself” (by Yu.N. Vavilov), which seems to be an optimal tool for determining biological age indicators. The purpose of the study is to find and analyze the effective methods of reduction of the indicators of the biological age of university students based on the integration of motor and cognitive activities in the process of physical education. The following research methods were used: analysis of scientific and methodological literature, physical fitness tests, and the methods of mathematical statistics. The sample included first-year students from two different faculties, whose motor activities were aimed at reducing the indicators of biological age. The respondents had been acquainted with the following aspects of the “Test Yourself” chart: calculation of the general level of physical condition and chart drawing and determination of the indicators of biological age. Furthermore, the students were asked to follow a developed program for reducing the indicators of biological age and were given a chance to choose an alternative plan of action in this direction. The analysis of the result of the students’ motor activity was oriented towards the establishment of the group average value of this indicator, which demonstrated a tendency to decrease. The cognitive activity within the course was oriented towards the formation of knowledge, skills and habits necessary to work with the “Test Yourself” chart. It was found out that the process of physical education aimed at reduction of the indicators of biological age makes it possible to increase not only the physical activity of university students but also the cognitive one.